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Description

This paper demonstrates that growing mammary epithelial 3D cultures, as well as highly proliferative human breast cancers, rely on aminotransferases downstream of glutamine metabolism for biosynthesis, whereas quiescent cells instead express GLUD

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The new biology and pharmacology of glucagon

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Adult mice lacking Folr1 had lower blood folate levels and higher renal folate clearance rate ( 4 FR in ovarian cancer FR is normally expressed in fallopian tube but not the ovary, consistent with EOC originating from the fallopian tube fimbriae rather than from ovary epithelial cells ( in vivo and in vitro ( 4.1 FR as transporter It has been proposed that FR promotes tumorigenesis by increasing folates for one-carbon metabolism ( 4.2 FR as transcription factor Once entering cells by endocytosis, FR and associated FA can activate several cellular pathways

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